http://www.sciepub.com/journal/WJOC World Journal of Organic Chemistry is a peer-reviewed, open access journal that provides rapid publication of articles in all areas of organic chemistry. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of organic chemistry. Science and Education Publishing en 2013 Science and Education Publishing Co. Ltd All rights reserved. World Journal of Organic Chemistry 12 1 January 2025 2013 Science and Education Publishing Co. Ltd All rights reserved. http://pubs.sciepub.com/wjoc/12/1/1 Terminalia avicennioides is a plant widely used in the Central African Republic for the treatment of numerous pathologies with anti-inflammatory components. The main objective of this study was to identify the chemical constituents and evaluate the antioxidant and antibacterial activities of Terminalia avicennioides root bark extracts. The phytochemical study showed that the methanolic extract was the best extraction solvent with a yield of 21.78%. Qualitative analysis revealed the presence of flavonoids, tannins, saponins, sterols and triterpenes. Quantitative analysis showed that the methanolic extract had a high total phenolic content, i.e. 2149 ± 1391,10 mg EqAG/g Ms. Evaluation of the free radical scavenging capacity of methanolic extracts of Terminala. avicennioides using the DPPH method gave a moderate IC₅₀ value with an R² = 0,75. The antimicrobial activity against Staphylococcus aureus and Escherichia coli was studied using the diffusion method. The zone of inhibition, inhibitory concentration and minimum bactericidal concentration of the extracts on the organisms were evaluated. The methanolic extract inhibited the growth of E. coli and S. aureus with MICs between 0,45-4,00 µg/mL and MBCs between 4,50-22,2 µg/mL. The root bark of T. avicennioides showed significant antibacterial activity due to its high content of polyphenolic compounds.]]> Issa-Madongo Mathurin, Ngaïssona Paul., Worowounga Xavier, Namkona Frederic Armel, Ouefio Mboïssio Angelique, Saravolia Marinette, Gbayonnon Eugene, Koane Jean Noel, Syssa-Magalé Jean Laurent 2025-02-04 Science and Education Publishing 2025-02-04 1 12 1 7 10.12691/wjoc-12-1-1 http://pubs.sciepub.com/wjoc/12/1/2 Ipomea muricata, a species of Togolese flora that is not well known for its therapeutic properties. The main goal of this study is to promote the use of I. muricata seed oil in food, cosmetics, pharmaceuticals, or bioenergy. After extracting the oil from the kernels of this plant's seeds using the Soxhlet method, its physicochemical characteristics and mineral content were determined in accordance with AFNOR and Codex Alimentarius standards. The chemical profile of the fatty acids in the oil was established by GC-MS analysis. The oil was converted into biodiesel by transesterification process. The transesterification reaction was catalyzed in a homogeneous phase using KOH as a basic catalyst. The results revealed that the oil content in the kernel was approximately 13.16 ± 0.87%. The physicochemical parameters of the extracted oil are: refractive index (1.46153 ± 0.00100); water and volatile matter content (12.162 ± 5.838%); acid value: (8.987 ± 0.202 mg KOH/g); saponification value (168.250 ± 4.220 mg KOH/g); ester index (159.26 ± 4.018 mg KOH/g); iodine index (38.065 ± 0.005 g I₂/100 g); peroxide index (7.320 ± 0.001 µg O₂/g); relative density at 29°C (90.730 ± 0.001); volumic density at 29°C (0.9074 ± 0.0010 g/L, and calorific value (41.040 ± 0.162 MJ/kg). The results also showed that the oil is a significant source of: sodium (56.67 mg/L), iron (16.67 mg/L), potassium (11.33 mg/L), calcium (4.33 mg/L), and manganese (1.83 mg/L). The biodiesel produced is characterized by a lower refractive index and density, compared to the crude vegetable oil used in its production. Generally, the results confirmed that I. muricata seed oil owns promising characteristics for its use in food, cosmetics, or bioenergy. However, apart from the kernel, the other parts of the seed could also contain biomolecules of therapeutic interest that should be explored to optimize the value of this seed.]]> Kosi Mawuéna Novidzro, Yaovi Raoul Amouzouvi, Mamatchi Melila, Kossi Honoré Koumaglo 2025-10-26 Science and Education Publishing 2025-10-26 1 12 8 19 10.12691/wjoc-12-1-2 http://pubs.sciepub.com/wjoc/12/1/3 Introduction: Dichapetalum guineense is an underexplored leafy vegetable traditionally used in West Africa for both food and medicinal purposes. Despite its ethnobotanical importance, little is known about its nutritional and phytochemical properties. This study aimed to characterize the phytochemical profile and evaluate the nutritional potential of its leaves. Methods: Leaves of D. guineense were collected in Lomé, Togo, dried, powdered, and subjected to aqueous, ethanolic, and hydroethanolic extractions. Standard qualitative phytochemical tests were performed, while proximate composition, energy value, and mineral contents were determined following AOAC methods. Safety assessment included the analysis of antinutritional factors. Results: Phytochemical screening revealed the presence of flavonoids, tannins, saponins, reducing sugars, and terpenoids in all extracts, whereas alkaloids, coumarins, anthocyanins, and mucilages were absent. Nutritional analysis showed high calcium (763 mg/100 g DM, ≈ 85% RDA), magnesium (162 mg/100 g DM, ≈ 39% RDA), and iron (5.68 mg/100 g DM, up to 21% RDA), with zinc levels (7.63 mg/100 g DM) exceeding those of spinach and moringa. The Na/K ratio was favorable for hypertension prevention. The leaves also contained 11.9 g/100 g DM of protein, 13.2 g/100 g DM of lipids, 25.7 g/100 g DM of dietary fiber, and very low digestible carbohydrates (2.2 g/100 g DM), yielding a moderate energy value of 278 Kcal/100 g DM. Cyanides and nitrites were absent. Conclusion: D. guineense leaves are nutrient-dense, with high protein, mineral, and fiber content, suggesting utility as a functional food for addressing malnutrition, anemia, and hypertension in sub-Saharan Africa. Their complementary composition compared to spinach and moringa further supports their integration into diets and nutraceutical applications.]]> Kodjo Selom EVENAMEDE, Mamatchi MELILA, Essowè Badanèzi POTCHO, Komi Michael Fulbert ADANLEMEGBE, Mawaté Florance BRUKUM, Kafui KPEGBA, Oudjaniyobi SIMALOU 2025-11-01 Science and Education Publishing 2025-11-01 1 12 20 25 10.12691/wjoc-12-1-3